Top AI Talks to Watch at HIMSS25: How Artificial Intelligence is Reshaping Healthcare

The HIMSS25 Global Health Conference & Exhibition is set to take place from March 3-6, 2025, in Las Vegas, Nevada, bringing together healthcare professionals, IT experts, government officials, and industry leaders to explore the latest innovations in health information and technology. Among the most anticipated discussions at this year's event are those focusing on the transformative role of artificial intelligence (AI) in healthcare. From interoperability to cybersecurity and patient-centered care, AI is driving rapid advancements in the industry.

With an exhibition hall featuring over 1,000 leading healthcare companies and innovative startups, attendees will have access to the latest technologies revolutionizing the field. Among the conference's standout AI-focused presentations, these are the top sessions healthcare leaders should watch at HIMSS25:

1. The Next Interoperability Challenge – Accurate Information Retrieval

Speaker: Mika Newton, CEO of xCures

When: Tuesday, March 4, 2025 | 3:00 PM – 3:20 PM (US/Pacific)

Where: Smart Theatre in the Interoperability and Smart Experience Pavilion, Caesars Forum

The healthcare industry has made significant strides in interoperability, allowing seamless access to patient medical records. However, clinicians now face a new challenge—too much data, too little clarity. Mika Newton will address the need for AI-driven solutions that sift through massive volumes of patient data to surface the most relevant, actionable insights. As AI continues to play a role in data retrieval, ensuring its accuracy and eliminating AI hallucinations will be crucial for clinical decision-making. Newton will share insights from his experience in cancer patient data aggregation, demonstrating how validated AI-driven retrieval can enhance trust in healthcare decision-making.

2. Adopting, Adapting, and Advancing: Harnessing the Power of Cyber and AI

Speaker: General Paul Nakasone, Former Commander, U.S. Cyber Command & Former Director, NSA

When: Wednesday, March 5, 2025 | 8:30 AM – 9:45 AM (US/Pacific)

Where: Venetian | Level 2 | Venetian F

Cybersecurity and AI are deeply intertwined as healthcare organizations work to protect sensitive patient data while leveraging AI to improve healthcare outcomes. General Paul Nakasone, former head of the National Security Agency (NSA) and U.S. Cyber Command, will lead a keynote session exploring the importance of cybersecurity in AI adoption. Drawing from his experience leading cyber operations against nation-state threats, he will provide insights into how AI can be used to fortify digital defenses, prevent cyber threats, and protect sensitive patient information.

3. Shaping the Future of Healthcare: A Collaborative Care Journey Where Technology and Humanity Coexist

Speakers: Dr. Seung Woo Park, President, Samsung Medical Center & Dr. Meong Hi Son, Chief Medical Information Officer

When: Tuesday, March 4, 2025 | 8:30 AM – 10:00 AM (US/Pacific)

Where: Venetian | Level 2 | Venetian F

In an era where AI-driven automation is reshaping healthcare, Samsung Medical Center’s Dr. Seung Woo Park and Dr. Meong Hi Son will explore the intersection of technology and human-centered care. This keynote will highlight Samsung’s Digital Health Transformation strategy, including its AI-powered DARWIN platform, designed to enhance Electronic Medical Records (EMR) and improve patient outcomes. The session will also emphasize the importance of balancing technological innovation with compassionate care, ensuring AI is used to support, rather than replace, human decision-making in healthcare.

4. At the Intersection of Life Sciences and Healthcare: Holistic Opportunities to Improve Patient-Centered Care

Speaker: Seema Verma, Executive VP & General Manager, Oracle Health & Life Sciences

When: Wednesday, March 5, 2025 | 12:45 PM – 1:45 PM (US/Pacific)

Where: Venetian | Level 2 | Venetian F

Seema Verma, a leader in healthcare innovation, will discuss how AI and data science are converging to enhance patient-centered care. This session will explore how AI is driving personalized medicine, improving clinical workflows, and helping clinicians make more informed treatment decisions. The conversation will also highlight how interoperability and AI-driven analytics can improve healthcare sustainability and affordability while addressing pressing healthcare challenges.

5. Artificial Intelligence in Healthcare: Medical Research Applications and Considerations

Speaker: James Angle, Product Manager, Trinity Health

When: Wednesday, March 5, 2025 | 2:00 PM – 3:00 PM (US/Pacific)

Where: Venetian | Level 3 | Lido 3104

AI has revolutionized drug discovery and medical research, accelerating breakthroughs in diagnostics and treatment. James Angle will examine how AI-powered tools are transforming clinical research, reducing development timelines, and improving medical trial efficiency. However, with AI adoption come challenges, including regulatory hurdles, data exchange limitations, and provider adoption barriers. This session will provide a comprehensive overview of AI’s impact on medical research and how the industry can overcome key obstacles to maximize AI’s potential.

6. The Use of Digital Health and Artificial Intelligence for Rehabilitation

Speaker: Andi Saptono, Assistant Professor, University of Pittsburgh

When: Wednesday, March 5, 2025 | 1:30 PM – 2:00 PM (US/Pacific)

Where: Venetian | Level 5 | Palazzo M

AI is playing a growing role in rehabilitation and long-term patient care. In this session, Andi Saptono will present cutting-edge AI applications developed by the Health and Rehabilitation Informatics Lab (HARI LAB). These solutions include AI-powered remote patient monitoring, mHealth apps, and self-management support tools designed to improve rehabilitation outcomes. The discussion will also cover the opportunities and challenges in integrating AI into long-term patient care, extending the benefits of rehabilitation beyond hospital walls.

Final Thoughts

AI is undoubtedly a driving force in the healthcare industry, offering unprecedented opportunities to improve patient care, optimize workflows, and enhance clinical decision-making. From cybersecurity and medical research to interoperability and patient-centered AI solutions, the discussions at HIMSS25 will shape the future of healthcare technology.

Whether you're a clinician, researcher, IT expert, or policymaker, these sessions offer invaluable insights into the evolving role of AI in healthcare. With Las Vegas set to host one of the most significant gatherings in health tech, HIMSS25 promises to be an event where industry leaders can collaborate, innovate, and advance the future of healthcare together.